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Intoxication Anosognosia:
The Spellbinding Effect of
Psychiatric Drugs
Peter R. Breggin, MD
Ithaca, NY
Why do so many individuals persist in taking psychoactive substances, including psychiatric
drugs, after adverse mental and behavioral effects have become severe and even
disabling? The author has previously proposed the brain-disabling principle of psychiatric
treatment that all somatic psychiatric treatments impair the function of the brain and
mind. Intoxication anosognosia (medication spellbinding) is an expression of this druginduced
mental disability. Intoxication anosognosia causes the victim to underestimate
the degree of drug-induced mental impairment, to deny the harmful role that the drug
plays in the person’s altered state, and in many cases compel the individual to mistakenly
believe that he or she is functioning better. In the extreme, the individual displays outof-
character compulsively destructive behaviors, including violence toward self and others.
Keywords: adverse drug effects; psychiatric medications; drug-induced cognitive
deficits; toxicology; substance abuse
spellbinding_psychiatric_drugs.pdf (207683 B)