Sugar is Toxic to Mice in ‘Safe’ Doses | University of Utah News
http://unews.utah.edu/news_releases/sugar-is-toxic-to-mice-in-safe-doses/
When mice ate a diet of 25 percent extra sugar – the mouse equivalent of a healthy human diet plus three cans of soda daily – females died at twice the normal rate and males were a quarter less likely to hold territory and reproduce, according to a toxicity test developed at the University of Utah.
“Our results provide evidence that added sugar consumed at concentrations currently considered safe exerts dramatic adverse impacts on mammalian health,” the researchers say in a study set for online publication Tuesday, Aug. 13 in the journal Nature Communications.
“This demonstrates the adverse effects of added sugars at human-relevant levels,” says University of Utah biology professor Wayne Potts, the study’s senior author. He says previous studies using other tests fed mice large doses of sugar disproportionate to the amount people consume in sweetened beverages, baked goods and candy.
Even though the mice didn’t become obese and showed few metabolic symptoms, the sensitive test showed “they died more often and tended to have fewer babies,” says the study’s first author, James Ruff, who recently earned his Ph.D. at the University of Utah. “We have shown that levels of sugar that people typically consume – and that are considered safe by regulatory agencies – impair the health of mice.”